1 基本信息：

陈心悦，女，汉族，bwin必赢青年研究员，硕士生导师。2012年本科毕业于中国药科大学，2016年硕士毕业于兰州大学药物分析学专业，2019年博士毕业于中国科学院兰州化学物理研究所分析化学专业，2019年在兰州大学化学流动站从事“师资博士后”研究，2023年受聘为bwin必赢青年研究员。近年来研究领域为：1）新型光学比色传感器的构建及光谱法在药物分析化学中的应用；2）中药化学成分的空间分布、药效活性及体内药物代谢研究。目前主持完成中国博士后基金第66批面上项目、国家药监局中药材及饮片质量控制重点实验室项目，参与完成国家自然科学基金科研项目5项。以第一作者/通讯作者在Sensors & Actuators: B. Chemical、Talanta、Microchemical Journal、Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy、Journal of food composition and analysis等国际知名期刊发表SCI学术论文19篇，一区、二区论文共计13篇，申请国家发明专利3项。

2 以第一作者/通讯作者发表论文：

(1) Xin-Yue Chen; Run-tian Ma; Wei Ha*; Yan-ping Shi*; Direct colorimetric detection of aspartic acid in rat brain based on oriented aggregation of Janus gold nanoparticle, Sensors & Actuators: B. Chemical, 2018, 274: 668-675.

(2) Xin-Yue Chen; Wei Ha*; Yan-Ping Shi*; Sensitive colorimetric detection of melamine in processed raw milk using asymmetrically PEGylated gold nanoparticles, Talanta, 2018, 194: 475-484.

(3) Xinyue Chen; Dan Liu; Sanhu Gou; Jiahui Ji; Zhiyuan Xue; Shilan Feng*; A novel and sensitive colorimetric detection of PABA by asymmetrically functionalized TA-AuNPs-PEG-FITC based on oriented aggregation, Advanced Powder Technology, 2021, 32(10): 3540-3549.

(4) Xin-Yue Chen; Wei Ha*; Xiao-Jie Jin; Yan-Ping Shi*; PEGylated NALC-functionalized gold nanoparticles for colorimetric discrimination of chiral tyrosine, Analyst, 2020, 145: 7397-7405.

(5) Xinyue Chen; Dan Liu; Huifang Wu; Jiahui Ji; Zhiyuan Xue; Shilan Feng*; Sensitive determination of tobramycin using homocystine capped gold nanoclusters as probe by second-order scattering, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 270: 120840.

(6)Xin-Yue Chen; Jia-Hui Ji; Dong-Han Wang; San-Hu Gou; Zhi-Yuan Xue; Liang-Gong Zhao*; Shi-Lan Feng*; Highly sensitive and selective colorimetric sensing of histidine by NAC functionalized AuNPs in aqueous medium with real sample application, Microchemical Journal, 2021, 160: 105661-105671.

(7) Xin-Yue Chen; San-Hu Gou; Zhi-Qiang Shi; Zhi-Yuan Xue; Shi-Lan Feng*; Spectrum-effect relationship between HPLC fingerprints and bioactive components of Radix Hedysari on increasing the peak bone mass of rat, Journal of Pharmaceutical Analysis, 2019, 9: 266-273.

(8) Xin-Yue Chen; Zhi-Yuan Xue; Jia-Hui Ji; Dong-Han Wang; Gen-Gen Shi; Liang-Gong Zhao*; Shi-Lan Feng*; Hedysarum polysaccharides mediated green synthesis of gold nanoparticles and study of its characteristic, analytical merit, catalytic activity, Materials Research Bulletin, 2021, 133: 111070-111081.

(9) Xin-Yue Chen; Jia-Hui Ji; Gen-Gen Shi; Zhi-Yuan Xue; Xiang-Lin Zhou, Liang-Gong Zhao*; Shi-Lan Feng*; Formononetin in Radix Hedysari extract-mediated green synthesis of gold nanoparticles for colorimetric detection of ferrous ions in tap water, RSC Advances, 2020, 10: 32897-32905.

(10) Xin-yue Chen, Wei Ha*, Yan-ping Shi*. Sensitive colorimetric detection of Al using asymmetrically PEGylated gold nanoparticles. Chinese Journal of Analytical Chemistry, 2019, 47(5): 709-718.

(11) Jiahui Ji, Huifang Wu, Donghan Wang, Dan Liu, Xinyue Chen*, Shilan Feng*. Green Synthesized Silver Nanoparticles for Colorimetric Detection of Pb2+ in Yellow River Medium, Analytical Methods, 2022, 14, 643-651.

(12) Dan Liu, Yilan Zhao, Jiahui Ji, Xiaohua Liu, Shilan Feng*, Xinyue Chen*. Design of fluorescence system based on rutin functionalized gold nanoparticles: Sensitive detection of etimicin via a smartphone in the food and human samples, Arabian Journal of Chemistry, 2022, 15, 12, 104325.

(13) Dan Liu, Ruizhuo Lin, Huifang Wu, Jiahui Ji, Donghan Wang, Zhiyuan Xue, Shilan Feng*, Xinyue Chen*. Green synthesis, characterization of procyanidin-mediated gold nanoparticles and its application in fluorescence detection of prazosin, Microchemical Journal, 2022, 173, 107045.

(14) Jiahui Ji, Lianggong Zhao, Xiaohua Liu, Huifang Wu, Donghan Wang, Dan Liu, Xinyue Chen*, Shilan Feng*, Green synthesis, characterization of formononetin mediated AgNPs and its testing for formothion in typical fruit and vegetable samples, Journal of Food Composition and Analysis, 2022, 112, 104572.

(15) Xin-Ran Guo, Yu-Ming Dong, Xinyue Chen*, Juan Chen*, Sophora japonica L. flower mediated carbon dots with nitrogen and sulfur co-doped as a sensitive fluorescent probe for amoxicillin detection, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 282: 121730.

(16) Dan Liu †, Jiahui Ji †, Xinran Guo, Sanhu Gou and Xinyue Chen*, Syringe Paper-Based Analytical Device for Thiamazole Detection by Hedysarum Polysaccharides-Mediated Silver Nanoparticles, Micromachines, 2023, 14, 250.

(17) Yifei Kong, Dan Liu, Xinran Guo and Xinyue Chen*, Fluorescence detection of three types of pollutants based on fluorescence resonance energy transfer and its comparison with colorimetric detection, RSC Advances, 2023, 13, 22043.

(18) Dan Liu, Xinran Guo, Huifang Wu, Xinyue Chen*, Aggregation-induced emission enhancement of gold nanoclusters triggered by sodium heparin and its application in the detection of sodium heparin and alkaline amino acids, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2024, 304, 123255.

(19) Xinran Guo, Yanxin Guo and Xinyue Chen*, The Brown Sugar Mediated Carbon Quantum Dots as a Novel Fluorescence Sensor for Sensitive Detection of Gentamicin and Its Application in Foods, International Journal of Molecular Sciences, 2024, 25, 2143.

(20) 陈心悦; 李继平; 柳小亚; 陈亚丽; 洪妍; 封士兰*; 红芪多糖对 CCl4致小鼠肝纤维化及骨丢失的防治作用, 中草药, 2016, 47(2): 290-296. (CSCD)

(21) 陈心悦，柳小亚，陈亚丽，洪妍，封士兰*.红芪药材防治肝纤维化的谱效关系, 色谱, 2015, 4（33）：413-418. （CSCD）

(22) 陈心悦，哈伟，师彦平*.“两面神”型金纳米粒子比色检测铁离子的新方法，分析测试学报，2019, 38（05），574-580.（CSCD）

3 已授权专利：

(1) 封士兰，赵良功，陈心悦，柳小亚.红芪乙醇提取物在制备预防和治疗肝纤维化药物和保健品中的应用及其中有效成分鉴定方法[P]. CN104706708

(2) 师彦平; 哈伟; 赵晓博; 姜侃; 陈心悦，一种用于联合用药的喜树碱前药负载双药物超分子水凝胶的制备方法[P]. CN107714641A